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Dear UBC,
It is our pleasure to provide you again with some fresh news and updates from the UBC community. In this newsletter, Dr. Belen Rabaglino will introduce herself to our community. Earlier this month, she presented her exciting work during a UBC in-person seminar. Dr. Rabaglino talked about the relevance of pregnancy failure in cattle and how she is using omics techniques, bioinformatics, and machine learning to tackle this societal and scientific problem.
In the next couple of months, several UBC-related events are planned. On 27th May, we are organising our very first industry market. This is especially aimed at Master’s students and PhD candidates interested in learning about bioinformatics research at companies on Utrecht Science Park. Next up is a seminar by Dr. Kimberley Siletti from UMC Utrecht, on 8th April. Also coming up is the 10th edition of the UBC symposium! We aim to organize the event this autumn. We will provide more details as soon as possible.
As always, we are excited to facilitate connections among the UBC bioinformatics community and are eager to hear news from across the USP.
Ronnie de Jonge
On behalf of the UBC daily board
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Meet UBC Principal Investigator Belen Rabaglino
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| Continuing our series of introducing UBC's principal investigators, we sat down with veterinary scientist Belen Rabalio. In this interview, Belen provides a peek into her research work on the intersection of veterinary science and bioinformatics, with a focus on cattle reproduction. Her work relies on transcriptomics and epigenomics to decode the biology of uterus tissue and embryonic development. Bioinformatics tools have proven to be crucial to unravel complex data, offering insights into animal health and tailored treatments. Belen also calls for interdisciplinary collaboration, and bridging disciplines to drive innovation. |
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Jeroen de Ridder featured in Nature |
A Nature Technology Feature highlights how the race to revolutionize genomic diagnosis has hit overdrive. The article features, UBC member Jeroen de Ridder, amongst others. Jeroen spearheads a sequencing-based approach slashing brain tumor diagnosis time to under 90 minutes from biopsy collection. Read the full Nature feature for an insight into this genomic revolution.
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NVE Prize for Stefan Prekovic |
UBC member Stefan Prekovic received an NVE Prize for his research paper recently published in EMBO Molecular Medicine. The prize was awarded by the Dutch Association for Endocrinology (NVE). Stefan's article outlines how the glucocorticoid receptor (GR) affects a type of breast cancer known as luminal subtype and interacts with estrogen receptor (ER) to control gene expression. Congratulations Stefan!
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Vici grants for Jop Kind and Puck Knipscheer |
| UBC members Jop Kind and Puck Knipscheer, both working at the Hubrecht Institute, receive Vici grants from the Dutch Research Council. Kind explores gene positioning in embryonic development, while Knipscheer investigates obstacles in DNA replication. Both receive up to 1.5 million euros to expand their work and develop new innovative research lines. |
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Recent publications by UBC members |
Genotype-dependent N-glycosylation and newly exposed O-glycosylation affect plasmin-induced cleavage of histidine-rich glycoprotein (HRG)
Journal of Biological Chemistry, Volume 300, Issue 3, March 2024
Albert Heck's group
Segmental duplications drive the evolution of accessory regions in a major crop pathogen
New Phytologist, 25 February 2024
Michael Seidl's group
Ultraconserved bacteriophage genome sequence identified in 1300-year-old human palaeofaeces
Nature Communications, Volume, 23 January 2024
Bas Dutilh's group
Ultralong transients enhance sensitivity and resolution in Orbitrap-based single-ion mass spectrometry
Nature Methods, 5 March 2024
Albert Heck's group
Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer
Cancer Cell, Volume, 42, Issue 3, 11 March 2024
Ruben van Boxtel's group |
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UBC Seminar: Molecular architecture of mammalian brains |
In the next UBC Seminar, Kimberly Siletti will share with us the latest developements surrounding her groundbreaking research on the molecular architecture of the mammalian brain. Learn about the thousands of cell types across brain regions and their implications for understanding brain function and disease. No registration needed. Join us for this enlightening seminar followed by networking over drinks.
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Bioinformatics Industry Career Day |
Explore bioinformatics careers at the UBC Industry Career Day on May 27, featuring companies based on Utrecht Science Park, like GenDx, The Hyve, and Cyclomics. Join us for elevator pitches, interactive discussions, and walk-in sessions. The event aims to provide a sneak peek into diverse career paths and possible future collaborations in bioinformatics. It is particularly aimed at Master's students and PhD candidates, but we welcome all students and researchers interested in bioinformatics.
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Tenth edition of the UBC Annual Symposium coming up |
| This year's edition of the UBC Annual Symposium is set to take place in October 2024. It promises to be a memorable event, as we will be celebrating our tenth anniversary of this symposium! While October may seem distant, the UBC Board is diligently working to secure the optimal location and date for this milestone event. Stay tuned for updates as we finalize the exact date and other details. |
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